Applied Biosystems

Sigma-Aldrich Joins Phase 2 of the RNAi Consortium to Validate shRNA Libraries
Sigma-Aldrich to provide full functional validation data for its MISSION® shRNA collection.

Invitrogen Scientists Link microRNA Sequences to Cancer Using RNA Samples from BioServe
Invitrogen and BioServe technologies have identified noncoding RNAs that were differentially expressed in healthy and diseased tissue.

LC Sciences and DNAVision form Strategic Marketing Alliance
Agreement aims at increasing accessibility to LC Sciences’ custom microRNA profiling service to researchers in Europe.

Regulus Therapeutics Exclusively Licenses Intellectual Property from Stanford University
Regulus gains right to patent applications covering methods and compositions for antagonizing miR-181a to regulate immune responses.

Getting Wise to the Influenza Virus’s Tricks
A high-resolution image of an influenza virus protein opens the way to design new anti-viral drugs.

Diagnostic Significance of microRNA Tumor Biomarkers in Fine Needle Aspirates (FNA) of Pancreatic Cancer
Asuragen, Inc., Dartmouth Medical School and Dartmouth Hitchcock Medical Center

Collection of pancreatic fine needle aspirates (FNAs) in RNARetain™ allows stabilization and protection of RNA in tissues containing high levels of nucleases; Differential miRNA expression in pancreatic FNAs accurately classifies benign and malignant tissue; Combinations of miRNA and mRNA expression signatures improve the separation between normal tissue and chronic pancreatitis; microRNAs are suitable analytes for molecular characterization of fine needle aspirates from pancreatic tissues.

Apoptosis Inducing Novel microRNA for Breast cancer and Hepatocellular Carcinoma
UC Davis Medical Center

MicroRNA provides a mechanism to target cancer stem cells and restraint tumors cells permanently; this could lead to promising cancer therapeutics and imaging agents. Apoptosis inducing microRNA was identified to target HCC and breast cancer cells for imaging and therapy.

A genome-wide loss of function screen identifies new genes required for lung cancer cell proliferation
CNRS

RNA interference (RNAi) provides an experimental tool for functional genomics analysis. We screened a genome-wide RNAi library to identify new genes involved in lung cancer cell proliferation. 72 % from the 257 genes identified were involved in general gene expression processes, 16 % were of unknown function or unrelated to proliferation, and 12% consisted of uncharacterized genes. These last sets of genes provide potential novel targets for lung cancer treatment.

Permanent Senior Scientist Position in NMR-based Metabolomics
CIBERDEM
Tarragona, Spain

BBSRC Funded Microfluidics Engineering Resarch PhD
University College London
London, UK

Post-Doctpral Position in Mollusk Health Laboratory
UPEI
Charlottetown, Canada

Production Chemist II
Independent
Torrance, CA, USA

Research Chemist
Independent
Torrance, CA, USA

phD Scholarship in BioInformatics
Universitat Rovira i Virgili
Tarragona, Spain

QC Analyst
Genomic Health
Redwood City, CA, USA

Research Scientist II - Biology
Gilead Sciences
Foster City, CA, USA

High Throughput Coordinator / Engineer
AJI
Houston, TX, USA

Assistant Director, Automation Services
Medarex, Inc.
Milpitas, CA, USA

IBC’s TIDES®: Oligonucleotide and Peptide® Technology and Product Development, Las Vegas, NV, USA
18 May 2008 - 21 May 2008

TIDES® is the all encompassing conference on manufacturing, formulation, delivery, process and analytical development, as well as overall market trends for peptides and oligonucleotides. In addition to gaining scientific updates in conference sessions, you can develop and maintain your professional skills with two tracks focusing on oligos and peptides.

Lead-Finding Screening, London, UK
19 May 2008 - 21 May 2008

Enhance your lead discovery strategy and produce the quality leads you want by choosing the right assays and follow-up tools.

RNAi, siRNA & miRNA, London, UK
11 June 2008 - 12 June 2008

The SMi Group are proud to present their 3rd RNAi, siRNA and miRNA 2008 conference. This conference offers a unique opportunity to hear about the latest developments from both industry leaders and academic research. The conference will address developments in understanding biology of RNAi and its potential applications in gene function analysis and therapy, as well as siRNA and the fascinating new developments in the world of miRNAs.

Virtual Discovery Europe, Amsterdam, The Netherlands
19 June 2008 - 20 June 2008

This is the second annual Virtual Discovery Europe conference and exhibition. This meeting will be focusing on computer-aided drug design and screening. Topics to be covered are Virtual Screening, Computational Chemistry, Lead Identification and Optimisation, New Algorithms and Technologies and Chemoinformatics. Confirmed speakers are Prof. Wolfgang Sippl from Martin Luther University and Prof. Maurizio Botta of the University of Siena.
  


Targeting c-Jun and JunB Proteins as Potential Anti-Cancer Cell Therapy

Marta Izquierdo, Professor of Biochemistry and Molecular Biology, Autonomous University of Madrid, speaking at RNAi Europe 2007



MISSIONTM RNAi: Using siRNA and shRNA to Mediate Gene Silencing

Heather Holemon, R&D Principle Investigator, Functional Genomics Group, Sigma-Aldrich, speaking at RNAi Europe 2007

Formulations for Using Dicer-Substrate siRNA in vivo

Mark Behlke, Vice President, Molecular Genetics, Integrated DNA Technologies, speaking at RNAi Europe 2007

MicroRNA 2008
Published January 2008

This report presents an exhaustive analysis of all the products and services offered by the various vendors into the microRNA market. Select Biosciences' proprietary market surveys addressed the qualitative and quantitative trends in the microRNA research market in terms of challenges, opportunities, and quantitative industry metrics—all the raw data and analyses based on the data are presented. In addition to the microRNA research market, this report also addresses the industry dynamics/trends

RNAi Therapeutics 2008
Published November 2007

An exhaustive analysis of all the current RNAi therapeutics candidates in various clinical trial stages, a detailed market survey with a view of all therapeutic areas where RNAi therapeutics are expected to impact, drug targets amenable to RNAi therapeutics, druggability factors of RNAi-based therapeutics, a detailed analysis of technologies in RNAi, as well as the intellectual property (IP) landscape of RNAi-based therapeutics space.